[{"data":1,"prerenderedAt":207},["ShallowReactive",2],{"drug-clindamycin-vaginal":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":34,"contraindications":53,"warnings":63,"renal":64,"monitoring":65,"interactions":66,"review":67,"examples":70,"atc":71,"iran":73,"links":141,"populations":160,"usApproval":202},"clindamycin-vaginal",1,{"fa":7,"en":8},"کلیندامایسین کرم واژینال","Clindamycin vaginal cream","genitourinary-sex-hormones",{"fa":11,"en":12},"آنتی‌بیوتیک واژینال","Vaginal antibiotic",[14],{"name":15,"market":16},"Clindesse","US",[18,19,20],"clindesse","cleocin vaginal","کرم کلیندامایسین واژینال",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":29,"refs":30},"app-5","vaginal-cream","vaginal","2% cream, 5 g single-dose applicator (100 mg)",{"amount":5,"unit":28,"perUnit":28},"application",[16],[31],{"source":32,"section":33},"fda-clindesse","3",[35],{"id":36,"disease":37,"label":38,"population":41,"type":42,"unit":43,"dose":44,"refs":48},"bv","bacterial-vaginosis",{"fa":39,"en":40},"واژینوز باکتریایی (غیرباردار) — یک اپلیکاتور یک‌بار","Bacterial vaginosis (non-pregnant) — one applicator once",{},"notCalculated","mg",{"reason":45},{"fa":46,"en":47},"کل محتوای یک اپلیکاتور (۵ گرم) یک بار داخل واژن در هر ساعت از روز.","The entire contents of one 5 g applicator once intravaginally at any time of day.",[49,51],{"source":32,"section":50},"2",{"source":32,"section":52},"1",[54],{"id":55,"severity":56,"text":57,"refs":60},"ci","block",{"fa":58,"en":59},"حساسیت به کلیندامایسین یا لینکوزامیدها؛ سابقه انتریت ناحیه‌ای، کولیت اولسراتیو یا اسهال C. difficile.","Hypersensitivity to clindamycin or lincosamides; history of regional enteritis, ulcerative colitis or C. difficile diarrhoea.",[61],{"source":32,"section":62},"4",[],[],[],[],{"status":68,"reviewer":69,"date":69},"unverified",null,[],[72],"G01AA10",{"status":74,"forms":75,"refs":136},"registered",[76,80,84,88,92,96,100,104,108,112,116,120,124,128,132],{"code":77,"en":78,"fa":79},"00311","CLINDAMYCIN _ BULK","ماده اولیه کلیندامایسین",{"code":81,"en":82,"fa":83},"08522","CLINDAMYCIN 100MG VAG TAB","قرص واژینال کلیندامایسین ۱۰۰ میلی‌گرم",{"code":85,"en":86,"fa":87},"15142","CLINDAMYCIN 100MG VAGINAL SUPP","شیاف کلیندامایسین ۱۰۰ میلی‌گرم",{"code":89,"en":90,"fa":91},"09464","CLINDAMYCIN 300MG CAP","کپسول کلیندامایسین ۳۰۰ میلی‌گرم",{"code":93,"en":94,"fa":95},"17383","CLINDAMYCIN 32G 80ML FOR SUSP","سوسپانسیون کلیندامایسین ۳۲ گرم ۸۰ میلی‌لیتر",{"code":97,"en":98,"fa":99},"00309","CLINDAMYCIN HCL 150MG CAP","کپسول کلیندامایسین هیدروکلراید ۱۵۰ میلی‌گرم",{"code":101,"en":102,"fa":103},"14328","CLINDAMYCIN HCL 80ML SYRUP","شربت کلیندامایسین هیدروکلراید ۸۰ میلی‌لیتر",{"code":105,"en":106,"fa":107},"01435","CLINDAMYCIN PALMITATE 75G\u002F5ML 100ML SUSP","سوسپانسیون کلیندامایسین پالمیتات ۷۵ گرم \u002F ۵ میلی‌لیتر ۱۰۰ میلی‌لیتر",{"code":109,"en":110,"fa":111},"01862","CLINDAMYCIN PHOSPHATE 1% 15G GEL","ژل کلیندامایسین فسفات ۱ درصد ۱۵ گرم",{"code":113,"en":114,"fa":115},"01374","CLINDAMYCIN PHOSPHATE 1% 60ML TOP SOLUTION","محلول کلیندامایسین فسفات ۱ درصد ۶۰ میلی‌لیتر",{"code":117,"en":118,"fa":119},"02234","CLINDAMYCIN PHOSPHATE 2% 40G VAG CREAM","کرم واژینال کلیندامایسین فسفات ۲ درصد ۴۰ گرم",{"code":121,"en":122,"fa":123},"01947","CLINDAMYCIN PHOSPHATE 300MG\u002F2ML AMP","آمپول کلیندامایسین فسفات ۳۰۰ میلی‌گرم \u002F ۲ میلی‌لیتر",{"code":125,"en":126,"fa":127},"11753","CLINDAMYCIN PHOSPHATE 600MG\u002F4ML AMP","آمپول کلیندامایسین فسفات ۶۰۰ میلی‌گرم \u002F ۴ میلی‌لیتر",{"code":129,"en":130,"fa":131},"52088","CLINDAMYCIN (AS PALMITATE HYDROCHLORIDE) SUSPENSION ORAL 75 mg\u002F5mL 100 mL","سوسپانسیون خوراکی کلیندامایسین (معادل پالمیتات هیدروکلراید) ۷۵ میلی‌گرم \u002F ۵ میلی‌لیتر ۱۰۰ میلی‌لیتر",{"code":133,"en":134,"fa":135},"52451","CLINDAMYCIN (AS PALMITATE HYDROCHLORIDE) POWDER, FOR SOLUTION ORAL 75 mg\u002F5mL 80 mL","محلول خوراکی کلیندامایسین (معادل پالمیتات هیدروکلراید) ۷۵ میلی‌گرم \u002F ۵ میلی‌لیتر ۸۰ میلی‌لیتر",[137],{"source":138,"section":139,"url":140},"darooyab-generic","G-366\u002FClindamycin","https:\u002F\u002Fwww.darooyab.ir\u002FG-366\u002FClindamycin",[142,146,150,154,157],{"kind":143,"url":144,"label":145},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=050793","NDA050793",{"kind":147,"url":148,"label":149},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=fe8bb204-f173-44fe-803b-b08f2ec5aa31","FDA Clindesse",{"kind":151,"url":152,"label":153},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa609006.html","Clindamycin Vaginal",{"kind":155,"url":156,"label":72},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G01AA10",{"kind":158,"url":140,"label":159},"darooyab","Clindamycin",{"pregnancy":161,"lactation":170,"pediatric":178,"geriatric":186,"reproductive":194},{"level":162,"text":163,"quote":166,"refs":167},"caution",{"fa":164,"en":165},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Clindesse has not been studied in pregnant women.",[168],{"source":32,"section":169},"8.1",{"level":162,"text":171,"quote":174,"refs":175},{"fa":172,"en":173},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary The systemic exposure (based on AUC and C max ) of Clindesse is substantially lower than intravenous administration of clindamycin [see Clinical Pharmacology ( 12.3 )] ; therefore, adverse effects on the breastfed infant are not expected from transfer of clindamycin into breastmilk.",[176],{"source":32,"section":177},"8.2",{"level":162,"text":179,"quote":182,"refs":183},{"fa":180,"en":181},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and efficacy of Clindesse in the treatment of bacterial vaginosis in post-menarchal females have been established on the extrapolation of clinical trial data from adult women.",[184],{"source":32,"section":185},"8.4",{"level":162,"text":187,"quote":190,"refs":191},{"fa":188,"en":189},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Clinical studies with Clindesse did not include sufficient numbers of subjects 65 years of age or older to determine whether they respond differently than younger subjects.",[192],{"source":32,"section":193},"8.5",{"level":162,"text":195,"quote":198,"refs":199},{"fa":196,"en":197},"برچسب نکته‌ای درباره بارداری، پیشگیری یا باروری زنان و مردان دارد.","Label has advice on pregnancy testing, contraception or fertility for females and males.","Contraception Clindesse contains mineral oil that may weaken latex or rubber products such as condoms or vaginal contraceptive diaphragms.",[200],{"source":32,"section":201},"8.3",{"kind":203,"refs":204,"id":145},"NDA",[205],{"source":32,"section":206},"SPL approval \u002F marketing category",1792111449284]