[{"data":1,"prerenderedAt":218},["ShallowReactive",2],{"drug-cefoxitin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":19,"regimens":42,"contraindications":103,"warnings":113,"renal":121,"monitoring":131,"interactions":132,"review":133,"examples":136,"atc":152,"iran":154,"links":161,"populations":179,"usApproval":213},"cefoxitin",1,{"fa":7,"en":8},"سفوکسیتین","Cefoxitin","anti-infectives",{"fa":11,"en":12},"سفامایسین (سفالوسپورین نسل دوم)","Cephamycin (second-generation cephalosporin)",[14],{"name":15,"market":16},"Mefoxin","US",[18,7],"mefoxin",[20,34],{"id":21,"form":22,"route":23,"label":24,"concentration":25,"markets":29,"refs":30},"vial-1g","powder-for-injection","iv","1 g vial",{"amount":26,"unit":27,"perUnit":28},1000,"mg","vial",[16],[31],{"source":32,"section":33},"fda-cefoxitin","How Supplied",{"id":35,"form":22,"route":23,"label":36,"concentration":37,"markets":39,"refs":40},"vial-2g","2 g vial",{"amount":38,"unit":27,"perUnit":28},2000,[16],[41],{"source":32,"section":33},[43,66,84],{"id":44,"disease":45,"label":46,"population":49,"type":53,"unit":27,"dose":54,"refs":56,"notes":59},"std","intra-abdominal-infection",{"fa":47,"en":48},"عفونت بدون عارضه (پنومونی، UTI، پوست) — بزرگسال ۱ g هر ۶ تا ۸ ساعت","Uncomplicated infections (pneumonia, UTI, skin) — adult 1 g every 6–8 h",{"minAge":50},{"value":51,"unit":52},18,"year","fixed",{"perDose":26,"dosesPerDay":55},4,[57],{"source":32,"section":58},"Dosage and Administration — Table 1",[60],{"text":61,"refs":64},{"fa":62,"en":63},"متوسط تا شدید: ۱ g هر ۴ ساعت یا ۲ g هر ۶ تا ۸ ساعت (۶ تا ۸ g\u002Fروز)؛ گانگرن گازی: تا ۱۲ g\u002Fروز. روی کلامیدیا اثر ندارد.","Moderate–severe: 1 g every 4 h or 2 g every 6–8 h (6–8 g\u002Fday); gas gangrene: up to 12 g\u002Fday. No activity against chlamydia.",[65],{"source":32,"section":58},{"id":67,"disease":45,"label":68,"population":71,"type":76,"unit":27,"dose":77,"refs":81},"child",{"fa":69,"en":70},"کودک ۳ ماه به بالا — ۳۰ تا ۴۰ mg\u002Fkg هر ۶ تا ۸ ساعت","Children ≥3 months — 30–40 mg\u002Fkg every 6–8 h",{"minAge":72,"maxAge":75},{"value":73,"unit":74},3,"month",{"value":51,"unit":52},"weightBased",{"perKgPerDose":78,"perKgPerDoseMax":79,"intervalHours":80},30,40,6,[82],{"source":32,"section":83},"Dosage and Administration",{"id":85,"disease":86,"label":87,"population":90,"type":53,"unit":27,"dose":92,"refs":93,"durationDays":95,"notes":96},"cs","surgical-prophylaxis",{"fa":88,"en":89},"پیشگیری سزارین — ۲ g وریدی هنگام بستن بند ناف","Caesarean prophylaxis — 2 g IV when the cord is clamped",{"minAge":91},{"value":51,"unit":52},{"perDose":38,"dosesPerDay":5},[94],{"source":32,"section":83},{"min":5,"max":5},[97],{"text":98,"refs":101},{"fa":99,"en":100},"یا سه دوز ۲ g: هنگام بستن بند ناف و ۴ و ۸ ساعت بعد.","Or three 2 g doses: at cord clamping and 4 and 8 h later.",[102],{"source":32,"section":83},[104],{"id":105,"severity":106,"text":107,"refs":110},"hyper","block",{"fa":108,"en":109},"حساسیت به سفوکسیتین و سفالوسپورین‌ها.","Hypersensitivity to cefoxitin and cephalosporins.",[111],{"source":32,"section":112},"Contraindications",[114],{"text":115,"refs":118},{"fa":116,"en":117},"واکنش آلرژیک جدی؛ اسهال مرتبط با کلستریدیوئیدس دیفیسیل.","Serious hypersensitivity; Clostridioides difficile-associated diarrhoea.",[119],{"source":32,"section":120},"Warnings",[122],{"egfrBelow":123,"severity":124,"text":125,"refs":128},51,"warn",{"fa":126,"en":127},"ClCr ۳۰ تا ۵۰: ۱ تا ۲ g هر ۸ تا ۱۲ ساعت؛ کمتر طبق جدول ۲ برچسب.","CrCl 30–50: 1–2 g every 8–12 h; lower per label Table 2.",[129],{"source":32,"section":130},"Dosage and Administration — Table 2",[],[],{"status":134,"reviewer":135,"date":135},"unverified",null,[137,142,148],{"regimen":44,"formulation":21,"input":138,"expect":141},{"ageYears":139,"weightKg":140},50,70,{"perDose":26,"dosesPerDay":55},{"regimen":67,"formulation":21,"input":143,"expect":145},{"ageYears":80,"weightKg":144},20,{"perDose":146,"upperPerDose":147},600,800,{"regimen":85,"formulation":35,"input":149,"expect":151},{"ageYears":78,"weightKg":150},75,{"perDose":38},[153],"J01DC01",{"status":155,"refs":156},"not-found",[157],{"source":158,"section":159,"url":160},"darooyab-generic","G-338\u002FCefoxitin","https:\u002F\u002Fwww.darooyab.ir\u002FG-338\u002FCefoxitin",[162,166,170,174,177],{"kind":163,"url":164,"label":165},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=065414","ANDA065414",{"kind":167,"url":168,"label":169},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=658a0dc6-6da5-44dc-94f2-1211619297f7","FDA Cefoxitin",{"kind":171,"url":172,"label":173},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682737.html","Cefoxitin Injection",{"kind":175,"url":176,"label":153},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J01DC01",{"kind":178,"url":160,"label":8},"darooyab",{"pregnancy":180,"lactation":189,"pediatric":197,"geriatric":205},{"level":181,"text":182,"quote":185,"refs":186},"caution",{"fa":183,"en":184},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.",[187],{"source":32,"section":188},"Pregnancy",{"level":181,"text":190,"quote":193,"refs":194},{"fa":191,"en":192},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Caution should be exercised when Cefoxitin for Injection is administered to a nursing woman.",[195],{"source":32,"section":196},"Nursing Mothers",{"level":181,"text":198,"quote":201,"refs":202},{"fa":199,"en":200},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and efficacy in pediatric patients from birth to 3 months of age have not yet been established.",[203],{"source":32,"section":204},"Pediatric Use",{"level":181,"text":206,"quote":209,"refs":210},{"fa":207,"en":208},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","… should be taken in dose selection, and it may be useful to monitor renal function (see DOSAGE AND ADMINISTRATION and PRECAUTIONS).",[211],{"source":32,"section":212},"Geriatric Use",{"kind":214,"refs":215,"id":165},"ANDA",[216],{"source":32,"section":217},"SPL approval \u002F marketing category",1792191531906]