[{"data":1,"prerenderedAt":169},["ShallowReactive",2],{"drug-carvedilol":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":59,"contraindications":138,"warnings":148,"renal":149,"monitoring":150,"interactions":151,"review":152,"examples":155},"carvedilol",1,{"fa":7,"en":8},"کارودیلول","Carvedilol","cardiovascular",{"fa":11,"en":12},"بتابلاکر غیرانتخابی با اثر آلفا","Non-selective beta-blocker with alpha-1 blockade",[14],{"name":15,"market":16},"Coreg","US",[18,7,19],"coreg","کارودیلل",[21,35,43,51],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-3-125","tablet","oral","3.125 mg tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},3.125,"mg",false,[16],[32],{"source":33,"section":34},"fda-carvedilol","3",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"tab-6-25","6.25 mg tablet",{"amount":39,"unit":28,"perUnit":23,"scored":29},6.25,[16],[42],{"source":33,"section":34},{"id":44,"form":23,"route":24,"label":45,"concentration":46,"markets":48,"refs":49},"tab-12-5","12.5 mg tablet",{"amount":47,"unit":28,"perUnit":23,"scored":29},12.5,[16],[50],{"source":33,"section":34},{"id":52,"form":23,"route":24,"label":53,"concentration":54,"markets":56,"refs":57},"tab-25","25 mg tablet",{"amount":55,"unit":28,"perUnit":23,"scored":29},25,[16],[58],{"source":33,"section":34},[60,85,104,123],{"id":61,"disease":62,"label":63,"population":66,"type":70,"unit":28,"dose":71,"refs":73,"notes":76},"hf","heart-failure",{"fa":64,"en":65},"نارسایی قلبی — شروع ۳٫۱۲۵ mg دو بار در روز به مدت ۲ هفته","Heart failure — start 3.125 mg twice daily for 2 weeks",{"minAge":67},{"value":68,"unit":69},18,"year","fixed",{"perDose":27,"dosesPerDay":72},2,[74],{"source":33,"section":75},"2.1",[77],{"text":78,"refs":81},{"fa":79,"en":80},"در صورت تحمل به ۶٫۲۵، ۱۲٫۵ و ۲۵ mg دو بار، هر مرحله ≥۲ هفته. حداکثر ۵۰ mg دو بار در بیماران بالای ۸۵ kg با نارسایی خفیف تا متوسط. با غذا.","If tolerated, increase to 6.25, 12.5 and 25 mg twice daily, each step ≥2 weeks. Max 50 mg twice daily in patients >85 kg with mild–moderate HF. With food.",[82,83],{"source":33,"section":75},{"source":33,"section":84},"2",{"id":86,"disease":87,"label":88,"population":91,"type":70,"unit":28,"dose":93,"refs":94,"notes":97},"post-mi","acute-coronary-syndrome",{"fa":89,"en":90},"اختلال عملکرد بطن چپ پس از MI — شروع ۶٫۲۵ mg دو بار","LV dysfunction after MI — start 6.25 mg twice daily",{"minAge":92},{"value":68,"unit":69},{"perDose":39,"dosesPerDay":72},[95],{"source":33,"section":96},"2.2",[98],{"text":99,"refs":102},{"fa":100,"en":101},"افزایش به ۱۲٫۵ و سپس ۲۵ mg دو بار با فاصله ۳ تا ۱۰ روز.","Increase to 12.5 then 25 mg twice daily at 3–10 day intervals.",[103],{"source":33,"section":84},{"id":105,"disease":106,"label":107,"population":110,"type":70,"unit":28,"dose":112,"refs":113,"notes":116},"htn","hypertension",{"fa":108,"en":109},"فشار خون — شروع ۶٫۲۵ mg دو بار در روز","Hypertension — start 6.25 mg twice daily",{"minAge":111},{"value":68,"unit":69},{"perDose":39,"dosesPerDay":72},[114],{"source":33,"section":115},"2.3",[117],{"text":118,"refs":121},{"fa":119,"en":120},"پس از ۷ تا ۱۴ روز در صورت نیاز ۱۲٫۵ و سپس ۲۵ mg دو بار.","After 7–14 days if needed 12.5 then 25 mg twice daily.",[122],{"source":33,"section":115},{"id":124,"disease":62,"label":125,"population":128,"type":130,"unit":28,"dose":131,"refs":135},"peds",{"fa":126,"en":127},"زیر ۱۸ سال","Under 18 years",{"maxAge":129},{"value":68,"unit":69},"notCalculated",{"reason":132},{"fa":133,"en":134},"بی‌خطری و اثربخشی در کودکان ثابت نشده است.","Safety and effectiveness in pediatric patients not established.",[136],{"source":33,"section":137},"8.4",[139],{"id":140,"severity":141,"text":142,"refs":145},"asthma","block",{"fa":143,"en":144},"آسم برونشیال یا بیماری‌های برونکواسپاستیک (و سایر موارد بخش ۴).","Bronchial asthma or related bronchospastic conditions (and other items in section 4).",[146],{"source":33,"section":147},"4",[],[],[],[],{"status":153,"reviewer":154,"date":154},"unverified",null,[156,161,166],{"regimen":61,"formulation":22,"input":157,"expect":160},{"ageYears":158,"weightKg":159},60,75,{"perDose":27,"tabletsPerDoseRounded":5},{"regimen":105,"formulation":36,"input":162,"expect":165},{"ageYears":163,"weightKg":164},50,80,{"perDay":47},{"regimen":86,"formulation":36,"input":167,"expect":168},{"ageYears":158,"weightKg":164},{"perDose":39},1792078532645]