[{"data":1,"prerenderedAt":140},["ShallowReactive",2],{"drug-carboprost":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":34,"contraindications":58,"warnings":68,"renal":76,"monitoring":77,"interactions":78,"review":79,"examples":82,"atc":88,"iran":90,"links":102,"populations":116,"usApproval":135},"carboprost",1,{"fa":7,"en":8},"کاربوپروست","Carboprost","genitourinary-sex-hormones",{"fa":11,"en":12},"پروستاگلاندین منقبض‌کننده رحم","Uterotonic prostaglandin",[14],{"name":15,"market":16},"Hemabate","US",[18,19,7],"hemabate","همابیت",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":29,"refs":30},"amp-250","injection","im","250 mcg\u002FmL (1 mL) ampoule",{"amount":27,"unit":28,"perVolumeMl":5},250,"mcg",[16],[31],{"source":32,"section":33},"fda-carboprost","How Supplied",[35],{"id":36,"disease":37,"label":38,"population":41,"type":45,"unit":28,"dose":46,"refs":47,"durationDays":50,"notes":51},"pph","postpartum-hemorrhage",{"fa":39,"en":40},"خونریزی مقاوم پس از زایمان — ۲۵۰ mcg عضلانی عمیق","Refractory postpartum haemorrhage — 250 mcg deep IM",{"minAge":42},{"value":43,"unit":44},18,"year","fixed",{"perDose":27,"dosesPerDay":5},[48],{"source":32,"section":49},"Dosage and Administration — 2. Refractory Postpartum Uterine Bleeding",{"min":5,"max":5},[52],{"text":53,"refs":56},{"fa":54,"en":55},"بیشتر موارد با یک تزریق جواب می‌دهند؛ در صورت نیاز تکرار با فاصله ۱۵ تا ۹۰ دقیقه. مجموع حداکثر ۲ mg (۸ دوز).","Most respond to a single injection; repeat at 15–90 min intervals if needed. Total max 2 mg (8 doses).",[57],{"source":32,"section":49},[59],{"id":60,"severity":61,"text":62,"refs":65},"ci","block",{"fa":63,"en":64},"حساسیت به کاربوپروست؛ PID حاد؛ بیماری فعال قلبی، ریوی، کلیوی یا کبدی.","Hypersensitivity to carboprost; acute PID; active cardiac, pulmonary, renal or hepatic disease.",[66],{"source":32,"section":67},"Contraindications",[69],{"text":70,"refs":73},{"fa":71,"en":72},"فقط با دوز دقیق و در بیمارستان با امکان مراقبت ویژه و جراحی فوری.","Strictly at recommended doses, in a hospital with immediate intensive care and surgery.",[74],{"source":32,"section":75},"Warnings",[],[],[],{"status":80,"reviewer":81,"date":81},"unverified",null,[83],{"regimen":36,"formulation":22,"input":84,"expect":87},{"ageYears":85,"weightKg":86},28,70,{"perDose":27,"mlPerDose":5},[89],"G02AD04",{"status":91,"forms":92,"refs":97},"registered",[93],{"code":94,"en":95,"fa":96},"18333","CARBOPROST 250 MCG  AMP.","آمپول کاربوپروست ۲۵۰ میکروگرم .",[98],{"source":99,"section":100,"url":101},"darooyab-generic","G-3177\u002FCarboprost","https:\u002F\u002Fwww.darooyab.ir\u002FG-3177\u002FCarboprost",[103,107,111,114],{"kind":104,"url":105,"label":106},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=216882","ANDA216882",{"kind":108,"url":109,"label":110},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=6ae32fdb-e0a9-4742-a90a-5c32ad9269ff","FDA Carboprost",{"kind":112,"url":113,"label":89},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G02AD04",{"kind":115,"url":101,"label":8},"darooyab",{"pregnancy":117,"pediatric":126},{"level":118,"text":119,"quote":122,"refs":123},"avoid",{"fa":120,"en":121},"برچسب: دارو برای ختم بارداری و خونریزی پس از زایمان است، نه بارداری ادامه‌دار؛ ختم ناموفق باید با روش دیگری تکمیل شود.","Label: used for pregnancy termination and postpartum haemorrhage, not in an ongoing pregnancy; a failed termination must be completed by other means.","Although these studies do not indicate that carboprost tromethamine injection is teratogenic, any pregnancy termination with carboprost tromethamine injection that fails should be completed by some other means.",[124],{"source":32,"section":125},"CONTRAINDICATIONS",{"level":127,"text":128,"quote":131,"refs":132},"not-established",{"fa":129,"en":130},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[133],{"source":32,"section":134},"Pediatric Use",{"kind":136,"refs":137,"id":106},"ANDA",[138],{"source":32,"section":139},"SPL approval \u002F marketing category",1792111447107]