[{"data":1,"prerenderedAt":175},["ShallowReactive",2],{"drug-benztropine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":42,"contraindications":87,"warnings":97,"renal":105,"monitoring":106,"interactions":107,"review":108,"examples":111,"atc":117,"iran":119,"usApproval":135,"links":141,"populations":157},"benztropine",1,{"fa":7,"en":8},"بنزتروپین","Benztropine","nervous-system",{"fa":11,"en":12},"آنتی‌کولینرژیک ضدپارکینسون","Anticholinergic antiparkinsonian",[14],{"name":15,"market":16},"Cogentin","US",[18,19,7],"cogentin","کوجنتین",[21,34],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":29,"refs":30},"tab-1","tablet","oral","1 mg tablet (scored)",{"amount":5,"unit":27,"perUnit":23,"scored":28},"mg",true,[16],[31],{"source":32,"section":33},"fda-benztropine","How Supplied",{"id":35,"form":23,"route":24,"label":36,"concentration":37,"markets":39,"refs":40},"tab-0-5","0.5 mg tablet (scored)",{"amount":38,"unit":27,"perUnit":23,"scored":28},0.5,[16],[41],{"source":32,"section":33},[43,72],{"id":44,"disease":45,"label":46,"population":49,"type":53,"unit":27,"dose":54,"refs":56,"limits":59,"notes":63},"eps","drug-induced-parkinsonism",{"fa":47,"en":48},"عوارض اکستراپیرامیدال ناشی از نورولپتیک — ۱ تا ۲ mg دو یا سه بار در روز","Neuroleptic-induced extrapyramidal disorders — 1–2 mg two or three times daily",{"minAge":50},{"value":51,"unit":52},3,"year","fixed",{"perDose":5,"perDoseMax":55,"dosesPerDay":55},2,[57],{"source":32,"section":58},"Dosage and Administration",{"maxPerDay":60,"refs":61},6,[62],{"source":32,"section":58},[64],{"text":65,"refs":68},{"fa":66,"en":67},"محدوده کلی ۱ تا ۴ mg یک یا دو بار. پس از ۱ تا ۲ هفته قطع برای سنجش نیاز. برای دیسکینزی دیررس نه.","Overall range 1–4 mg once or twice daily. Withdraw after 1–2 weeks to reassess. Not for tardive dyskinesia.",[69,70],{"source":32,"section":58},{"source":32,"section":71},"Indications and Usage",{"id":73,"disease":74,"label":75,"population":78,"type":80,"unit":27,"dose":81,"refs":85},"pd","parkinsons",{"fa":76,"en":77},"پارکینسونیسم ایدیوپاتیک یا پس از آنسفالیت (کمکی) — ۱ تا ۲ mg\u002Fروز (۰٫۵ تا ۶ mg)","Idiopathic or postencephalitic parkinsonism (adjunct) — 1–2 mg\u002Fday (0.5–6 mg)",{"minAge":79},{"value":51,"unit":52},"notCalculated",{"reason":82},{"fa":83,"en":84},"ایدیوپاتیک: شروع ۰٫۵ تا ۱ mg هنگام خواب؛ هر ۵ تا ۶ روز ۰٫۵ mg افزایش تا حداکثر ۶ mg. سالمند و افراد لاغر دوز بالا را تحمل نمی‌کنند.","Idiopathic: start 0.5–1 mg at bedtime; increase by 0.5 mg every 5–6 days to max 6 mg. Elderly and thin patients tolerate large doses poorly.",[86],{"source":32,"section":58},[88],{"id":89,"severity":90,"text":91,"refs":94},"ci","block",{"fa":92,"en":93},"حساسیت؛ کودک زیر ۳ سال (اثرات شبه‌آتروپین).","Hypersensitivity; children under 3 years (atropine-like effects).",[95],{"source":32,"section":96},"Contraindications",[98],{"text":99,"refs":102},{"fa":100,"en":101},"ایلئوس فلجی، هیپرترمی و گرمازدگی (گاه کشنده) به‌ویژه با فنوتیازین یا هالوپریدول؛ اختلال رانندگی.","Paralytic ileus, hyperthermia and heat stroke (sometimes fatal), especially with phenothiazines or haloperidol; impairs driving.",[103],{"source":32,"section":104},"Warnings",[],[],[],{"status":109,"reviewer":110,"date":110},"unverified",null,[112],{"regimen":44,"formulation":22,"input":113,"expect":116},{"ageYears":114,"weightKg":115},35,70,{"perDose":5,"tabletsPerDoseRounded":5,"upperPerDose":55},[118],"N04AC01",{"status":120,"forms":121,"refs":130},"registered",[122,126],{"code":123,"en":124,"fa":125},"00145","BENZTROPINE MESYLATE 2MG TAB","قرص بنزتروپین مزیلات ۲ میلی‌گرم",{"code":127,"en":128,"fa":129},"00144","BENZTROPINE MESYLATE 2MG\u002F2ML AMP","آمپول بنزتروپین مزیلات ۲ میلی‌گرم \u002F ۲ میلی‌لیتر",[131],{"source":132,"section":133,"url":134},"darooyab-generic","G-868\u002FBenztropine","https:\u002F\u002Fwww.darooyab.ir\u002FG-868\u002FBenztropine",{"kind":136,"refs":137,"id":140},"ANDA",[138],{"source":32,"section":139},"SPL approval \u002F marketing category","ANDA040715",[142,145,149,152,155],{"kind":143,"url":144,"label":140},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=040715",{"kind":146,"url":147,"label":148},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=c19664aa-a797-4192-b5f3-e906a7cac048","FDA Benztropine tabs",{"kind":150,"url":151,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682155.html",{"kind":153,"url":154,"label":118},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=N04AC01",{"kind":156,"url":134,"label":8},"darooyab",{"pediatric":158,"pregnancy":167},{"level":159,"text":160,"quote":163,"refs":164},"caution",{"fa":161,"en":162},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Because of the atropine-like side effects, benztropine mesylate should be used with caution in pediatric patients over three years of age (see CONTRAINDICATIONS ).",[165],{"source":32,"section":166},"Pediatric Use",{"level":159,"quote":168,"text":169,"refs":172},"مصرف در بارداری بنزتروپین گروه C در شرايط خاص و نظارت ويژه پزشك قابل استفاده است:",{"fa":170,"en":171},"دارویاب: گروه C — فقط اگر فایده بیشتر از خطر باشد.","Darooyab: category C — only if benefit outweighs risk.",[173],{"source":132,"section":174,"url":134},"G-868\u002FBenztropine — مصرف در بارداری",1792191528464]