[{"data":1,"prerenderedAt":220},["ShallowReactive",2],{"drug-anidulafungin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":43,"contraindications":118,"warnings":128,"renal":129,"monitoring":130,"interactions":131,"review":132,"examples":135,"atc":152,"iran":154,"usApproval":166,"links":172,"populations":185},"anidulafungin",1,{"fa":7,"en":8},"آنیدولافانژین","Anidulafungin","anti-infectives",{"fa":11,"en":12},"اکینوکاندین","Echinocandin",[14],{"name":15,"market":16},"Eraxis","US",[18,19,7],"eraxis","اراکسیس",[21,35],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"vial-100","powder-for-injection","iv","100 mg vial",{"amount":27,"unit":28,"perUnit":29},100,"mg","vial",[16],[32],{"source":33,"section":34},"fda-eraxis","3",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"vial-50","50 mg vial",{"amount":39,"unit":28,"perUnit":29},50,[16],[42],{"source":33,"section":34},[44,62,73,99],{"id":45,"disease":46,"label":47,"population":50,"type":54,"unit":28,"dose":55,"refs":57,"durationDays":60,"allowedFormulations":61},"load","invasive-fungal",{"fa":48,"en":49},"کاندیدمی — بزرگسال: روز اول بارگذاری ۲۰۰ mg","Candidaemia — adult: day 1 loading 200 mg",{"minAge":51},{"value":52,"unit":53},18,"year","fixed",{"perDose":56,"dosesPerDay":5},200,[58],{"source":33,"section":59},"2",{"min":5,"max":5},[22],{"id":63,"disease":46,"label":64,"population":67,"type":54,"unit":28,"dose":69,"refs":70,"allowedFormulations":72},"maint",{"fa":65,"en":66},"کاندیدمی — بزرگسال: ۱۰۰ mg روزانه از روز ۲، دست‌کم ۱۴ روز پس از آخرین کشت مثبت","Candidaemia — adult: 100 mg daily from day 2, ≥14 days after the last positive culture",{"minAge":68},{"value":52,"unit":53},{"perDose":27,"dosesPerDay":5},[71],{"source":33,"section":59},[22],{"id":74,"disease":46,"label":75,"population":78,"type":82,"unit":28,"dose":83,"refs":86,"limits":88,"allowedFormulations":91,"notes":92},"child",{"fa":76,"en":77},"کاندیدمی — کودک ۱ ماه به بالا: روز اول ۳ mg\u002Fkg (حداکثر ۲۰۰)، سپس ۱٫۵ mg\u002Fkg روزانه (حداکثر ۱۰۰)","Candidaemia — children ≥1 month: day 1 3 mg\u002Fkg (max 200), then 1.5 mg\u002Fkg daily (max 100)",{"minAge":79,"maxAge":81},{"value":5,"unit":80},"month",{"value":52,"unit":53},"weightBased",{"perKgPerDose":84,"intervalHours":85},1.5,24,[87],{"source":33,"section":59},{"maxPerDose":27,"refs":89},[90],{"source":33,"section":59},[36],[93],{"text":94,"refs":97},{"fa":95,"en":96},"عدد ماشین‌حساب دوز نگهدارنده است؛ روز اول ۳ mg\u002Fkg. سرعت انفوزیون حداکثر ۱٫۱ mg\u002Fدقیقه.","The calculator gives the maintenance dose; day 1 is 3 mg\u002Fkg. Infusion rate max 1.1 mg\u002Fmin.",[98],{"source":33,"section":59},{"id":100,"disease":101,"label":102,"population":105,"type":54,"unit":28,"dose":107,"refs":108,"allowedFormulations":110,"notes":111},"eso","esophageal-candidiasis",{"fa":103,"en":104},"کاندیدیاز مری — بزرگسال: روز اول ۱۰۰ mg سپس ۵۰ mg روزانه","Oesophageal candidiasis — adult: 100 mg day 1, then 50 mg daily",{"minAge":106},{"value":52,"unit":53},{"perDose":39,"dosesPerDay":5},[109],{"source":33,"section":59},[36],[112],{"text":113,"refs":116},{"fa":114,"en":115},"دست‌کم ۱۴ روز و ۷ روز پس از رفع علائم.","At least 14 days and 7 days after symptoms resolve.",[117],{"source":33,"section":59},[119],{"id":120,"severity":121,"text":122,"refs":125},"ci","block",{"fa":123,"en":124},"حساسیت به آنیدولافانژین یا اکینوکاندین‌ها؛ عدم تحمل ارثی فروکتوز (معلوم یا مشکوک).","Hypersensitivity to anidulafungin or other echinocandins; known or suspected hereditary fructose intolerance.",[126],{"source":33,"section":127},"4",[],[],[],[],{"status":133,"reviewer":134,"date":134},"unverified",null,[136,140,143,149],{"regimen":45,"formulation":22,"input":137,"expect":139},{"ageYears":39,"weightKg":138},70,{"perDose":56},{"regimen":63,"formulation":22,"input":141,"expect":142},{"ageYears":39,"weightKg":138},{"perDose":27},{"regimen":74,"formulation":36,"input":144,"expect":147},{"ageYears":145,"weightKg":146},6,20,{"perDose":148},30,{"regimen":100,"formulation":36,"input":150,"expect":151},{"ageYears":39,"weightKg":138},{"perDose":39},[153],"J02AX06",{"status":155,"forms":156,"refs":161},"registered",[157],{"code":158,"en":159,"fa":160},"15570","ANIDULAFUNGIN 100MG\u002F30ML INJ","فرآورده تزریقی آنیدولافانجین ۱۰۰ میلی‌گرم \u002F ۳۰ میلی‌لیتر",[162],{"source":163,"section":164,"url":165},"darooyab-generic","G-695\u002FAnidulafungin","https:\u002F\u002Fwww.darooyab.ir\u002FG-695\u002FAnidulafungin",{"kind":167,"refs":168,"id":171},"NDA",[169],{"source":33,"section":170},"SPL approval \u002F marketing category","NDA021632",[173,176,180,183],{"kind":174,"url":175,"label":171},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=021632",{"kind":177,"url":178,"label":179},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=a88d9010-55fb-4a02-baff-042cd27688ea","FDA Eraxis",{"kind":181,"url":182,"label":153},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J02AX06",{"kind":184,"url":165,"label":8},"darooyab",{"pregnancy":186,"lactation":195,"pediatric":204,"geriatric":212},{"level":187,"text":188,"quote":191,"refs":192},"avoid",{"fa":189,"en":190},"برچسب: می‌تواند به جنین آسیب بزند. در بارداری خطرناک است.","Label: can cause fetal harm. Dangerous in pregnancy.","Risk Summary Based on findings from animal studies, ERAXIS can cause fetal harm when administered to a pregnant woman.",[193],{"source":33,"section":194},"8.1",{"level":196,"text":197,"quote":200,"refs":201},"caution",{"fa":198,"en":199},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no data on the presence of anidulafungin in human milk, the effects on the breastfed infant or the effects on milk production.",[202],{"source":33,"section":203},"8.2",{"level":196,"text":205,"quote":208,"refs":209},{"fa":206,"en":207},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of ERAXIS for the treatment of candidemia and the following Candida infections: intra-abdominal abscess and peritonitis, have been established in pediatric patients 1 month of age and older.",[210],{"source":33,"section":211},"8.4",{"level":196,"text":213,"quote":216,"refs":217},{"fa":214,"en":215},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Of the total number of subjects (N = 197) in the pivotal clinical studies of anidulafungin, 35% were 65 years and over, while 18% were 75 years and over.",[218],{"source":33,"section":219},"8.5",1792191526124]