[{"data":1,"prerenderedAt":172},["ShallowReactive",2],{"drug-aminocaproic-acid":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":44,"contraindications":71,"warnings":80,"renal":88,"monitoring":89,"interactions":90,"review":91,"examples":94,"atc":100,"iran":102,"usApproval":118,"links":124,"populations":145},"aminocaproic-acid",1,{"fa":7,"en":8},"آمینوکاپروئیک اسید","Aminocaproic acid","blood",{"fa":11,"en":12},"ضدفیبرینولیز","Antifibrinolytic",[14],{"name":15,"market":16},"Amicar","US",[18,19,20],"amicar","آمیکار","آمینوکاپروئیک",[22,36],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-500","tablet","oral","500 mg tablet (scored)",{"amount":28,"unit":29,"perUnit":24,"scored":30},500,"mg",true,[16],[33],{"source":34,"section":35},"fda-aminocaproic","How Supplied",{"id":37,"form":24,"route":25,"label":38,"concentration":39,"markets":41,"refs":42},"tab-1000","1000 mg tablet (scored)",{"amount":40,"unit":29,"perUnit":24,"scored":30},1000,[16],[43],{"source":34,"section":35},[45],{"id":46,"disease":47,"label":48,"population":51,"type":55,"unit":29,"dose":56,"refs":58,"durationDays":61,"notes":62},"bleed","fibrinolytic-bleeding",{"fa":49,"en":50},"خونریزی حاد از فیبرینولیز زیاد — ساعت اول ۵ g، سپس ۱ g در ساعت حدود ۸ ساعت","Acute bleeding from elevated fibrinolysis — 5 g in the first hour, then 1 g per hour for about 8 h",{"minAge":52},{"value":53,"unit":54},18,"year","fixed",{"perDose":40,"dosesPerDay":57},8,[59],{"source":34,"section":60},"Dosage and Administration",{"min":5,"max":5},[63],{"text":64,"refs":67},{"fa":65,"en":66},"عدد ماشین‌حساب دوز ساعتی ۱ g است؛ ساعت اول ۵ g. تا کنترل خونریزی. فقط با تأیید فیبرینولیز اولیه، نه DIC.","The calculator gives the hourly 1 g dose; the first hour is 5 g. Continue until bleeding is controlled. Only with confirmed primary fibrinolysis, not DIC.",[68,69],{"source":34,"section":60},{"source":34,"section":70},"Contraindications",[72],{"id":73,"severity":74,"text":75,"refs":78},"dic","block",{"fa":76,"en":77},"شواهد فرایند انعقاد فعال داخل عروقی (DIC).","Evidence of an active intravascular clotting process (DIC).",[79],{"source":34,"section":70},[81],{"text":82,"refs":85},{"fa":83,"en":84},"خونریزی دستگاه ادراری فوقانی: خطر انسداد با لخته؛ میوپاتی و رابدومیولیز در مصرف طولانی.","Upper urinary tract bleeding: risk of obstructing clots; myopathy and rhabdomyolysis with prolonged use.",[86],{"source":34,"section":87},"Warnings",[],[],[],{"status":92,"reviewer":93,"date":93},"unverified",null,[95],{"regimen":46,"formulation":37,"input":96,"expect":99},{"ageYears":97,"weightKg":98},50,75,{"perDose":40,"tabletsPerDoseRounded":5},[101],"B02AA01",{"status":103,"forms":104,"refs":113},"registered",[105,109],{"code":106,"en":107,"fa":108},"02077","AMINOCAPROIC ACID 250MG\u002FML AMP","آمپول آمینوکاپروئیک اسید ۲۵۰ میلی‌گرم \u002F میلی‌لیتر",{"code":110,"en":111,"fa":112},"02078","AMINOCAPROIC ACID 4G\u002F10ML AMP","آمپول آمینوکاپروئیک اسید ۴ گرم \u002F ۱۰ میلی‌لیتر",[114],{"source":115,"section":116,"url":117},"darooyab-generic","G-1377\u002FAminocaproic-Acid","https:\u002F\u002Fwww.darooyab.ir\u002FG-1377\u002FAminocaproic-Acid",{"kind":119,"refs":120,"id":123},"ANDA",[121],{"source":34,"section":122},"SPL approval \u002F marketing category","ANDA213944",[125,128,132,136,139,142],{"kind":126,"url":127,"label":123},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=213944",{"kind":129,"url":130,"label":131},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=ae768406-955e-4863-9549-6c43662e5295","FDA Aminocaproic acid",{"kind":133,"url":134,"label":135},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa608023.html","Aminocaproic Acid",{"kind":133,"url":137,"label":138},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa608024.html","Aminocaproic Acid Injection",{"kind":140,"url":141,"label":101},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B02AA01",{"kind":143,"url":117,"label":144},"darooyab","Aminocaproic-Acid",{"pregnancy":146,"lactation":155,"pediatric":163},{"level":147,"text":148,"quote":151,"refs":152},"caution",{"fa":149,"en":150},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Animal reproduction studies have not been conducted with aminocaproic acid tablets.",[153],{"source":34,"section":154},"Pregnancy",{"level":147,"text":156,"quote":159,"refs":160},{"fa":157,"en":158},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because many drugs are excreted in human milk, caution should be exercised when aminocaproic acid tablets are administered to a nursing woman.",[161],{"source":34,"section":162},"Nursing Mothers",{"level":164,"text":165,"quote":168,"refs":169},"not-established",{"fa":166,"en":167},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[170],{"source":34,"section":171},"Pediatric Use",1792191525250]