[{"data":1,"prerenderedAt":181},["ShallowReactive",2],{"drug-amiloride":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":75,"warnings":85,"renal":93,"monitoring":94,"interactions":95,"review":96,"examples":99,"atc":109,"iran":111,"links":123,"populations":140,"usApproval":176},"amiloride",1,{"fa":7,"en":8},"آمیلوراید","Amiloride","cardiovascular",{"fa":11,"en":12},"دیورتیک نگهدارنده پتاسیم","Potassium-sparing diuretic",[14],{"name":15,"market":16},"Midamor","US",[18,7,19],"midamor","آمیلورید",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-5","tablet","oral","5 mg tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},5,"mg",false,[16],[32],{"source":33,"section":34},"fda-amiloride","How Supplied",[36,59],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":28,"dose":47,"refs":49,"notes":52},"htn","hypertension",{"fa":40,"en":41},"فشار خون (کمکی همراه تیازید) — ۵ mg روزانه، تا ۱۰ mg","Hypertension (adjunct to a thiazide) — 5 mg daily, up to 10 mg",{"minAge":43},{"value":44,"unit":45},18,"year","fixed",{"perDose":27,"perDoseMax":48,"dosesPerDay":5},10,[50],{"source":33,"section":51},"Dosage and Administration",[53],{"text":54,"refs":57},{"fa":55,"en":56},"همراه غذا. معمولاً همراه دیورتیک دفع‌کننده پتاسیم؛ تا ۱۰ mg (در هیپوکالمی پایدار تا ۱۵ تا ۲۰ mg با پایش الکترولیت).","With food. Usually added to a kaliuretic diuretic; up to 10 mg (15–20 mg for persistent hypokalaemia, with electrolyte monitoring).",[58],{"source":33,"section":51},{"id":60,"disease":61,"label":62,"population":65,"type":46,"unit":28,"dose":67,"refs":68,"notes":70},"hf","heart-failure",{"fa":63,"en":64},"نارسایی قلبی (کمکی همراه دیورتیک) — ۵ mg روزانه، تا ۱۰ mg","Heart failure (adjunct to a diuretic) — 5 mg daily, up to 10 mg",{"minAge":66},{"value":44,"unit":45},{"perDose":27,"perDoseMax":48,"dosesPerDay":5},[69],{"source":33,"section":51},[71],{"text":72,"refs":73},{"fa":55,"en":56},[74],{"source":33,"section":51},[76],{"id":77,"severity":78,"text":79,"refs":82},"ci","block",{"fa":80,"en":81},"پتاسیم بالای ۵٫۵؛ مصرف داروهای نگهدارنده پتاسیم دیگر (اسپیرونولاکتون، تریامترن) یا مکمل پتاسیم (جز هیپوکالمی شدید با پایش)؛ آنوری، نارسایی حاد یا مزمن کلیه، نفروپاتی دیابتی.","Serum potassium >5.5 mEq\u002FL; other potassium-conserving agents (spironolactone, triamterene) or potassium supplements (except severe hypokalaemia with monitoring); anuria, acute or chronic renal insufficiency, diabetic nephropathy.",[83],{"source":33,"section":84},"Contraindications",[86],{"text":87,"refs":90},{"fa":88,"en":89},"هیپرکالمی (پتاسیم بالای ۵٫۵) که اگر اصلاح نشود کشنده است؛ بدون دیورتیک دفع‌کننده پتاسیم حدود ۱۰٪ رخ می‌دهد.","Hyperkalaemia (K >5.5 mEq\u002FL), potentially fatal if uncorrected; occurs in about 10% without a kaliuretic diuretic.",[91],{"source":33,"section":92},"Warnings",[],[],[],{"status":97,"reviewer":98,"date":98},"unverified",null,[100,105],{"regimen":37,"formulation":22,"input":101,"expect":104},{"ageYears":102,"weightKg":103},60,75,{"perDose":27,"upperPerDose":48},{"regimen":60,"formulation":22,"input":106,"expect":108},{"ageYears":107,"weightKg":103},65,{"perDose":27,"upperPerDose":48},[110],"C03DB01",{"status":112,"forms":113,"refs":118},"registered",[114],{"code":115,"en":116,"fa":117},"07083","AMILORIDE 5MG TAB","قرص آمیلوراید ۵ میلی‌گرم",[119],{"source":120,"section":121,"url":122},"darooyab-generic","G-1520\u002FAmiloride","https:\u002F\u002Fwww.darooyab.ir\u002FG-1520\u002FAmiloride",[124,128,132,135,138],{"kind":125,"url":126,"label":127},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=070346","ANDA070346",{"kind":129,"url":130,"label":131},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=e0cc2d44-436a-47e8-a890-589882fff4c4","FDA Amiloride",{"kind":133,"url":134,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa615029.html",{"kind":136,"url":137,"label":110},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=C03DB01",{"kind":139,"url":122,"label":8},"darooyab",{"pregnancy":141,"lactation":150,"pediatric":159,"geriatric":168},{"level":142,"text":143,"quote":146,"refs":147},"caution",{"fa":144,"en":145},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Pregnancy Category B .",[148],{"source":33,"section":149},"Pregnancy",{"level":151,"text":152,"quote":155,"refs":156},"avoid",{"fa":153,"en":154},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from amiloride HCl, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[157],{"source":33,"section":158},"Nursing Mothers",{"level":160,"text":161,"quote":164,"refs":165},"not-established",{"fa":162,"en":163},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in pediatric patients have not been established.",[166],{"source":33,"section":167},"Pediatric Use",{"level":142,"text":169,"quote":172,"refs":173},{"fa":170,"en":171},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.",[174],{"source":33,"section":175},"Geriatric Use",{"kind":177,"refs":178,"id":127},"ANDA",[179],{"source":33,"section":180},"SPL approval \u002F marketing category",1792115167278]